Endocrine Abstracts

Primary squamous cell carcinoma of the thyroid gland (PSCCT) is a rare neoplasm of the thyroid with a poor prognosis. We present a 70-year-old male patient who presented with a progressively growing mass on the left side of the neck causing shortness of breath. The patient presented with suspicious poorly-differentiated malignancy as a result of the thyroid fine-needle aspiration cytology performed due to the rapidly growing mass. No other primary tumor focus was detected in t...

Background and Objectives: Leukocyte telomere length (LTL) is considered as a marker of cellular aging. Brown adipose tissue in women has been claimed to be associated with long life in women. Neuregulin-4 is a new batokine secreted from brown adipose tissue, and it is thought to play a role in the regulation of glucose, lipid metabolism and energy balance. The aim of the study is to examine LTL and serum Neuregulin-4 levels as well as their relations with disease activity, co...

Purpose: The liver is known to be protected from steatosis under the influence of high GH/IGF-1. Cytokeratin 18 (CK18) and insulin-like growth factor binding protein 7 (IGFBP7) increase in liver steatosis and fibrosis. Whether decreasing lipid content completely protects the liver from metabolic alterations and the response of CK18 and IGFBP7 to liver changes in acromegaly is unknown.Methods: This single-center, multidisciplinary, cross-sectional study i...

Background: Hypophysitis is a rare group of disease characterized with infla mmation of the pituitary gland. Rarity of the disease obviates development of a treatment strategy. We aimed to present the nationwide data of the demographics, clinical and radiological characteristics, treatment modalities and responses of the patients diagnosed with hypophysitis in a retrospective manner.Methods: The endocrinology clinics all over the country were invited to ...